Cox multivariable regression analyses of determinants of in-hospital mortality
Variables | HR | 95.0% CI | P value |
Age (tertiles) | |||
62–74 versus <62 years | 2.86 | 1.23 to 6.64 | 0.014 |
≥75 versus <62 years | 7.92 | 3.60 to 17.43 | <0.001 |
Number of comorbidities (tertiles) | |||
2–3 versus 0–1 | 1.85 | 1.11 to 3.08 | 0.018 |
≥4 versus 0–1 | 2.09 | 1.23 to 3.55 | 0.007 |
Respiratory rate (breaths/min), for unit increase | 1.04 | 1.02 to 1.07 | 0.001 |
PaO2/FiO2, for unit increase | 0.995 | 0.992 to 0.997 | <0.001 |
Creatinine (mg/dL), for unit increase | 1.34 | 1.18 to 1.51 | <0.001 |
Platelets (109/L), for unit increase | 0.995 | 0.992 to 0.998 | 0.001 |
History of cardiovascular disease, hypertension, diabetes, depression, dementia and cancer were included into ‘comorbidities’. Variables excluded (p>0.10) from both models: No. of drugs, Barthel Index, C reactive protein.