Table 3

Multivariate regression analysis of the impact of age, sex, intake of scheduled opioids and eGFR on mortality, readmission within 72 hours, rehospitalisation within 30 days and length of stay

	OR (95% CI; p)
	Mortality	Readmission within 72 hours	Rehospitalisation within 30 d	Length of stay (logarithmised), p value
Age	1.047 (1.036–1.059; <0.001)	0.989 (9.73–1.005; 0.17)	1.002 (0.994–1.009; 0.664)	<0.001
Sex	1.651 (1.292–2.110; <0.001)	0.76 (0.454–1.272; 0.296)	1.109 (0.884–1.390; 0.371)	0.496
Opioid intake	2.916 (2.193–3.876; <0.001)	2.543 (1.224–5.283; 0.012)	3.630 (2.771–4.755; <0.001)	<0.001
eGFR	0.980 (0.975–0.986; <0.001)	1.002 (0.990–1.014; 0.725)	0.986 (0.981–0.991; <0.001)	<0.001

Mortality depicts in-hospital mortality only. GFR was chosen as a surrogate marker for comorbidity as we did not systematically abstract comorbidities.
eGFR, estimated glomerular filtration rate.