Comparison of mortality and complications at intervention between MIS and OH cohorts
Unadjusted results | IPTW results | |||||||||||
MIS | OH | P value | MIS versus OH | MIS | OH | P value | MIS versus OH | |||||
No | % | No | % | OR (95% CI) | No | % | No | % | OR (95% CI) | |||
Death (intervention) | 9 | 0 | 18 | 0 | 0.007 | 0.35 (0.14 to 0.82) | 8 | 0 | 25 | 0 | 0.003 | 0.32 (0.12 to 0.73) |
Death (overall)* | 17 | 0 | 44 | 0 | <0.001 | 0.27 (0.14 to 0.48) | 15 | 0 | 44 | 0 | <0.001 | 0.34 (0.18 to 0.62) |
Any complication (intervention) | 4305 | 21 | 4012 | 28 | <0.001 | 0.54 (0.51 to 0.57) | 3503 | 21 | 4725 | 28 | <0.001 | 0.67 (0.64 to 0.71) |
Specific complications (intervention) | ||||||||||||
Gastrointestinal | 1637 | 8 | 1185 | 8 | <0.001 | 0.61 (0.57 to 0.66) | 1275 | 8 | 1479 | 9 | <0.001 | 0.85 (0.79 to 0.92) |
Wounds | 325 | 2 | 679 | 5 | <0.001 | 0.20 (0.17 to 0.23) | 276 | 2 | 783 | 5 | <0.001 | 0.34 (0.30 to 0.39) |
Infections | 360 | 2 | 815 | 6 | <0.001 | 0.16 (0.14 to 0.19) | 296 | 2 | 913 | 5 | <0.001 | 0.31 (0.27 to 0.36) |
Urinary | 623 | 3 | 786 | 5 | <0.001 | 0.26 (0.24 to 0.29) | 514 | 3 | 899 | 5 | <0.001 | 0.56 (0.50 to 0.62) |
Ureteric | 6 | 0 | 8 | 0 | 0.005 | 0.25 (0.07 to 0.82) | 4 | 0 | 8 | 0 | 0.247 | 0.50 (0.11 to 1.86) |
Cardiovascular | 1255 | 6 | 1162 | 8 | <0.001 | 0.30 (0.27 to 0.32) | 1047 | 6 | 1340 | 8 | <0.001 | 0.77 (0.70 to 0.83) |
Pulmonary | 305 | 1 | 587 | 4 | <0.001 | 0.13 (0.11 to 0.15) | 262 | 2 | 676 | 4 | <0.001 | 0.38(0.33 to 0.44) |
Neurological | 84 | 0 | 111 | 1 | <0.001 | 0.18 (0.14 to 0.24) | 77 | 0 | 120 | 1 | 0.002 | 0.64 (0.47 to 0.86) |
Haemorrhage | 199 | 1 | 270 | 2 | <0.001 | 0.17 (0.14 to 0.20) | 169 | 1 | 310 | 2 | <0.001 | 0.54 (0.44 to 0.65) |
Other | 736 | 4 | 646 | 5 | <0.001 | 0.22 (0.20 to 0.25) | 593 | 4 | 786 | 5 | <0.001 | 0.74 (0.67 to 0.83) |
*Death (overall) Includes death at intervention and deaths reported 90 days after intervention.
IPTW, inverse probability weighting of treatment; MIS, minimally invasive surgery; OH, open hysterectomy.