Timepoint PGI-I response | Oestrogen | No treatment | Relative risk (95% CI)‡ | |
6 weeks | n=42 | n=42 | ||
1=very much better | N (%) | 22 (52%) | 14 (33%) | |
2=much better | N (%) | 16 (38%) | 18 (43%) | |
3=a little better | N (%) | 4 (10%) | 8 (19%) | |
4=no change | N (%) | 0 (-) | 2 (5%) | |
5=a little worse | N (%) | 0 (-) | 0 (-) | |
6=much worse | N (%) | 0 (-) | 0 (-) | |
7=very much worse | N (%) | 0 (-) | 0 (-) | |
Better score* | N (%) | 42 (100%) | 40 (95%) | 1.05 (0.98 to 1.12) |
Worse score† | N (%) | 0 (-) | 2 (5%) | |
6 months | n=38 | n=41 | ||
1=very much better | N (%) | 13 (34%) | 18 (44%) | |
2=much better | N (%) | 16 (42%) | 17 (41%) | |
3=a little better | N (%) | 4 (11%) | 5 (12%) | |
4=no change | N (%) | 3 (8%) | 0 (-) | |
5=a little worse | N (%) | 2 (5%) | 1 (2%) | |
6=much worse | N (%) | 0 (-) | 0 (-) | |
7=very much worse | N (%) | 0 (-) | 0 (-) | |
Better score* | N (%) | 33 (87%) | 40 (98%) | 0.89 (0.78 to 1.02) |
Worse score† | N (%) | 5 (13%) | 1 (2%) | |
12 months | n=37 | n=42 | ||
1=very much better | N (%) | 14 (38%) | 17 (40%) | |
2=much better | N (%) | 15 (41%) | 17 (40%) | |
3=a little better | N (%) | 3 (8%) | 4 (10%) | |
4=no change | N (%) | 4 (11%) | 2 (5%) | |
5=a little worse | N (%) | 1 (3%) | 0 (-) | |
6=much worse | N (%) | 0 (-) | 2 (5%) | |
7=very much worse | N (%) | 0 (-) | 0 (-) | |
Better score* | N (%) | 32 (86%) | 38 (90%) | 0.96 (0.81 to 1.12) |
Worse score† | N (%) | 5 (14%) | 4 (10%) |
*Better score is derived from scores 1 (very much better) to 3 (a little better).
†Worse score is derived from scores 4 (no change) to 7 (very much worse).
‡>1 indicates better with oestrogen.