The GRADE classification of confidence in evidence ratings and its interpretation
| Confidence in evidence | Interpretation |
| High | Further research is very unlikely to change our confidence in the estimate of the effect. |
| Moderate | Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. |
| Low | Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. |
| Very low | We are very uncertain about the estimate. |
GRADE, Grading of Recommendations Assessment, Development and Evaluation.