First author | Study design | Publication year | Primary studies | n | Age (years) | Intervention investigated |
Liu33 | SR/MA RCTs | 2014 | 21 | 1421 | Range: 18–80 | Acupuncture |
Aminov8 | SR RCTs | 2018 | 4* | 97 | Mean: 62 | Virtual reality |
Braun29 | SR RCTs | 2013 | 3* | 115 | Mean: 70.7 | Mental practice |
Hoffmann16 | SR RCTs | 2011 | 1 | 33 | Mean: 72 | Occupational therapy |
Rogers31 | SR RCTs | 2018 | 22 | 1098 | Mean: 62 | Cognitive remediation; rehabilitation for multiple domains |
Tian37 | SR/MA RCTs | 2011 | 7* | 281 | Range: 37–43 | Transcranial magnetic stimulation |
das Nair9 | SR RCTs | 2016 | 13* | 514 | Range: 31–68 | Memory training in memory rehabilitation |
Loetscher32 | SR/MA RCTs | 2013 | 6 | 223 | Mean: 65 | Cognitive rehabilitation for attention deficits |
Hackett34 | SR RCTs | 2010 | 1* | 29 | Range: 57.8–73 | Antidepressant agents |
Jongstra38 | SR RCTs | 2016 | 1* | 1784 | Mean: 73 | Antihypertension withdrawal |
Mead39 | SR RCTs | 2012 | 7* | 425 | Range: 55–77 years | Selective serotonin reuptake inhibitor |
Yang40 | SR RCTs | 2015 | 1* | 62 | Range: 58–80 | Chinese herbal medicine—mailuoning |
Sami28 | SR RCTs | 2015 | 2* | 94 | RCT 1: mean 64† RCT 2: range 24–80‡ | Dopamine agonists |
Oberlin30 | SR/MA RCTs | 2017 | 14 | 736 | Mean: 62.5 | Aerobic exercise and stretching |
Pang35 | SR RCTs | 2013 | 1* | 38 | NA | Aerobic exercise and stretching |
Hayes36 | SR RCTs | 2016 | 3* | 159 | Mean: 62 | Cardiovascular |
Cumming26 | SR/MA RCTs | 2012 | 12 | 482 | Range: 41–79 | Active sessions |
Zheng27 | SR RCTs/CTs | 2016 | 10§ | 394 | Range: 45–77 | Aerobic exercise |
*Subset.
†Delbari et al.52
‡Gorgoraptis et al.53
§Six RCTs/four CTs.
CT, controlled trial; ; MA, meta-analysis; NA, not available; RCT, randomised controlled trial; SR, systematic review.