Table 2

Durations of respiratory support, oxygen therapy and hospitalisation in those who received intensive care

1991–92199720052016–2017*
n=332n=190n=229n=250
Median (IQR)Adj diff. medians (95% CI), p value†Median (IQR)Adj diff. medians (95% CI), p value†Median (IQR)Adj diff. medians (95% CI), p value†Median (IQR)
All respiratory support‡ (days), median (IQR)22 (4–41)−36 (−41 to –31), p<0.00142 (20–61)−24 (−31 to –18), p<0.00138 (16–69)−24 (−30 to −18), p<0.00166 (43–88) n=247
Invasive ventilation§ (days), median (IQR)16 (3–31)8 (4 to 12), p<0.00115 (4–30)4 (−1 to 9), p=0.0810 (2–27)2 (−3 to 7), p=0.409 (1–29) n=247
Non-invasive ventilation¶ (days), median (IQR)2 (0–9)−48 (−52 to –45), p<0.00121 (8–35)−30 (−34 to –26), p<0.00125 (6–40)−25 (−29 to –21), p<0.00151 (33–64) n=247
nCPAP (days), median (IQR)2 (0–9)−23 (−27 to –19), p<0.00121 (8–35)−4 (−9 to 0.3), p=0.0725 (6–40)0 (−4 to 4), p=0.9925 (9–39) n=247
HFNC (days), median (IQR)21 (11–31) n=247
Supplemental oxygen (days), median (IQR)43 (5–85) n=329−22 (−36 to –7), p=0.00447 (12–88) n=185−24 (−40 to –7), p=0.0157 (12–108) n=217−17 (−32 to –1), p=0.0474 (30–120) n=203
Primary hospital admission** (days), median (IQR)82 (19–104)−13 (−20 to –6), p<0.00193 (68–112)−9 (−17 to –1), p=0.0396 (72–128)−2 (−9 to 6), p=0.68100 (78–128) n=249
  • *2016–2017 cohort as a reference for all comparisons.

  • †Adjusted for inborn status (ie, birth in a tertiary perinatal centre), gestation at birth, sex, birthweight z-score.

  • ‡Includes positive pressure ventilation via endotracheal tube, high frequency oscillatory ventilation.

  • §Includes positive pressure ventilation via endotracheal tube, high frequency oscillatory ventilation, nCPAP and HFNC.

  • ¶Includes nCPAP and HFNC.

  • **Until discharge home.

  • Diff. medians, difference in medians; HFNC, high-flow nasal cannulae; nCPAP, nasal continuous positive airway pressure.