Health conditions addressed in the 100 Cochrane reviews assessed in relation to use of COS
| ICD-11 code | Disease area | N (%) |
| 12 | Respiratory system | 11 (11) |
| 16 | Genitourinary system | 11 (11) |
| 2 | Neoplasms | 9 (9) |
| 11 | Circulatory system | 8 (8) |
| 1 | Infectious or parasitic diseases | 5 (5) |
| 8 | Nervous system | 5 (5) |
| 13 | Digestive system | 4 (4) |
| 15 | Musculoskeletal system | 4 (4) |
| 9 | Visual system | 4 (4) |
| 14 | Skin | 3 (3) |
| 24 | Factors influencing health status or contact with health services | 3 (3) |
| 4 | Immune system | 2 (2) |
| 5 | Endocrine, nutritional or metabolic diseases | 2 (2) |
| 6 | Mental, behavioural or neurodevelopmental | 2 (2) |
| 7 | Sleep–wake disorders | 2 (2) |
| 17 | Conditions related to sexual health | 2 (2) |
| 3 | Blood or blood-forming organs | 1 (1) |
| 10 | Ear or mastoid process | 1 (1) |
| 19 | Certain conditions originating in the perinatal period | 1 (1) |
| 21 | Symptoms, signs or clinical findings, not elsewhere classified | 1 (1) |
| 22 | Injury, poisoning or certain other consequences of external causes | 1 (1) |
| 23 | External causes of morbidity or mortality | 1 (1) |
| No specific ICD-11 code | Miscellaneous | 17 (17) |
ICD-11, International Classification of Diseases 11th Revision.