Table 1

Patient population

SPECT
(n=1205)
CT
(n=625)
Revascularisation (n=210)Non-revascularisation
(n=995)
P valueRevascularisation
(n=149)
Non-revascularisation
(n=476)
P value
Age67.169.965.9410.70.12768.48.2965.2510.770.0011
Age ≥60 years old†16059.5%70583.3%0.12912684.6%33670.6%0.00059
Female6430.5%46446.6%<0.00015234.9%23950.2%0.00133
Height (cm)160.119.05159.199.120.182158.818.21158.519.030.719
Weight (Kg)62.5811.6560.4311.740.01661.7411.0960.0611.420.116
BMI (kg/m2)*†24.303.323.763.60.04624.373.4323.813.370.082
Systolic BP (mm Hg)139.8521.94137.2719.540.089140.7119.21138.7219.940.285
Diastolic BP (mm Hg)77.1313.3278.4912.010.14677.2410.9478.3212.770.355
Smoking5526.2%19419.5%0.0313825.5%9720.4%0.209
Hypertension†14066.7%53954.2%0.0019966.4%26255.0%0.017
Dyslipidaemia†11956.7%41341.5%<0.00018859.1%22346.8%0.011
Diabetes†10248.6%23723.8%<0.00016241.6%10421.8%<0.0001
Hyperuricaemia†157.1%494.9%0.234106.7%285.9%0.697
Familial history of CAD3215.2%11011.1%0.0992818.8%6714.1%0.190
Cerebrovascular
disease
2311.0%828.2%0.225138.7%245.0%0.111
Peripheral artery
disease
136.2%191.9%0.00132.0%30.6%0.151
Atrial fibrillation52.4%444.4%0.24632.0%173.6%0.434
COPD†31.4%101.0%0.48300.0%61.3%0.344
Disease of aorta41.9%222.2%1.00021.3%20.4%0.242
Malignancy62.9%232.3%0.62132.0%81.7%0.729
eGFR (mL/min/1.73 m2)†70.1325.3173.3930.970.15875.8518.4980.8936.920.109
Abnormal findings‡19492.4%35435.6%<0.000113691.3%13628.6%<0.0001
 SSS: 2~76028.6%24724.8%<0.0001n/an/an/an/a
 SSS: 8~†13463.8%10710.8%n/an/an/an/a
 SDS:>=217884.8%20620.7%<0.0001n/an/an/an/a
 1VDn/an/an/an/a6845.6%6814.3%<0.0001
 2VDn/an/an/an/a4328.9%357.4%
 3VD†n/an/an/an/a2516.8%153.2%
CCS†
 Class 111956.7%82082.4%<0.00016241.6%32468.1%<0.0001
 Class 28540.5%16516.6%7449.7%12526.3%
 Class 362.9%70.7%96.0%61.3%
 Class 400.0%30.3%42.7%214.4%
NYHA†
 I16980.5%93894.3%<0.000110973.2%39583.0%0.0003
 II3918.6%545.4%3221.5%5912.4%
 III21.0%30.3%42.7%71.5%
 IV00.0%00.0%42.7%153.2%
Subsequent CAG210100.0%19719.8%<0.0001149100.0%6613.9%<0.0001
 Obstructive CAD20899.0%484.8%0.001614899.3%398.2%<0.0001
Escalation of medical therapy210100.0%52753.0%<0.0001149100.0%28760.3%<0.0001
  • Values are number (%) or mean (SD).

  • P values were calculated from a χ2 test for categorical variables, Continuous variables were expressed as means (SD). Continuous variables were compared using the Student’s t-test between two groups.

  • *Body mass index was calculated as weight in kilograms divided by height in metres squared.

  • †Potential risk-adjusting variables selected for Cox proportional hazard models. CCS was adjusted for Class 2 or more, and NYHA functional class was adjusted for II or more.

  • ‡Abnormal findings were defined as SSS >2 in SPECT and >50% stenosis in segments 5, 6, 7, 11, 13, 1, 2 or 3 in CT.

  • BP, blood pressure; BMI, body mass index; CAD, coronary artery disease; CAG, coronary angiography; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular rate; CCS, Canadian Circulation Society; NYHA, New York Heart Association; SPECT, single photon emission CT; CT, CT tomography angiography; SSS, Summed Stress Score; SDS, Summed Difference Score; n/a, not available.