Patient demographic and clinical characteristics at index
| All enrolled patients (N=805) | Index stay | |||
| No infection (N=775) | Infection (N=30) | P value | ||
| Demographics | ||||
| Age (years), mean (SD) | 40.8 (17.2) | 40.7 (16.8) | 43.0 (23.9) | 0.61 |
| Gender, n (%) | 0.84 | |||
| Men | 590 (73.3) | 569 (73.4) | 21 (70.0) | |
| Clinical history/comorbidities | ||||
| Charlson score, median (range) | 0.00 (3.00) | 0.00 (2.00) | 0.00 (3.00) | <0.001 |
| Smoker, n (%) | 256 (31.8) | 247 (31.9) | 9 (30.0) | 0.99 |
| Diabetes, n (%) | 27 (3.4) | 27 (3.5) | 0 (0.0) | 0.62 |
| COPD, n (%) | 8 (1.0) | 8 (1.0) | 0 (0.0) | 1.00 |
| Congestive heart failure, n (%) | 2 (0.3) | 2 (0.3) | 0 (0.0) | 1.00 |
| Hypertension, n (%) | 12 (1.5) | 12 (1.6) | 0 (0.0) | 1.00 |
| Compartment syndrome, n (%) | 27 (3.4) | 22 (2.8) | 5 (16.7) | <0.01 |
| Index episode | ||||
| Inpatient waiting time (days) for surgery, mean (SD) | 1.4 (2.4) | 1.4 (2.4) | 0.70 (2.4) | 0.14 |
| Fracture type, n (%) | <0.001 | |||
| Open fracture | 142 (17.6) | 127 (16.4) | 15 (50.0) | |
| Received ≥1 prescription for antibiotics in the 12 months prior to the index stay, n (%) | 60 (7.5) | 60 (7.7) | 0 (0.00) | 0.16 |
| Received ≥1 prescription for opioids in the 12 months prior to the index stay, n (%) | 16 (2.0) | 15 (1.9) | 1 (3.3) | 0.46 |
COPD, chronic obstructive pulmonary disease.