Table 2

Underlying Causes of death in people With epilepsy 1999–2017

All deaths in people with epilepsy199920082017Per cent changeP value
161317864131
RankUnderlying cause of deathICD-10 codesNumber and proportion of deaths due to the underlying cause
1EpilepsyG40–G47845 (52.39%)881 (49.33%)1578 (38.19%)−27.1%<0.001
2Malignant neoplasmsC00–C9791 (5.64%)83 (4.64%)355 (8.59%)+52.3%<0.001
3Cerebrovascular diseaseI60–I69105 (6.51%)120 (6.72%)284 (6.87%)+5.5%0.62
4Ischaemic heart diseaseI20–I25174 (10.79%)123 (6.89%)256 (6.19%)−42.6%<0.001
5Degenerative diseases of the CNS (ie, Alzheimer’s)G30–G3124 (1.49%)55 (3.08%)195 (4.72%)+216.8%<0.001
6Cerebral palsyG80–G8328 (1.74%)52 (2.91%)149 (3.61%)+107.5%<0.001
7Organic mental disorders
(vascular dementia and delirium)
F01–F0916 (0.99%)35 (1.95%)127 (3.07%)+210.1%<0.001
  • Data are expressed as the number and proportion of deaths due to the underlying cause, Cochran-Armitage test for trend.

  • CNS, central nervous system; ICD, International Classification of Diseases.