Scenarios for various assumptions used in the sample size calculations
Assumptions | All cancers (based on lung cancer) | All cancers | All cancers | All cancers | Restricting to only 90th centile delays | Restricting to only 90th centile delays |
Median (days) | 14 | 14 | 60 | 60 | 60 | 60 |
Range (days) | 0–60 | 0–100 | 0–365 | 0–100 | 14–100 | 14–365 |
N of cancers per step per cluster | 9 | 9 | 9 | 9 | 1 | 1 |
Minimum detectable difference (days) | 2 | 5 | 13 | 4 | 9 | 39 |
Notes | Allowing greater range | Lower upper value for Primary Care Interval | Minimum set to median of all cancers | Min set to median of all cancers, but increased upper range |