Table 1

Example of treatment hierarchies from different ranking metrics for a network of nine antihypertensive treatment for primary prevention of cardiovascular disease

TreatmentOriginal dataFictional data with increased precision for conventional treatment versus ARB
Embedded ImageRanksEmbedded ImageRanksRelative treatment effect ranksEmbedded ImageRanksEmbedded ImageRanksRelative treatment effect ranks
Conventional163.5343.5
Diuretic/beta-blocker211111
ARB333.54.533.5
CCB422222
Alpha-blocker5774.577
ACE-inhibitor6456.555
Diuretic7566.566
Placebo8.5998.599
Beta-blocker8.5888.588
  • Relative treatment effect stands for the relative treatment effect against fictional treatment of average performance. The first three rankings from the left-hand side are obtained using the original data; the equivalent three rankings on the right-hand side are produced by reducing the standard error of the conventional versus ARB treatment effect from 0.7 to a fictional value of 0.01.

  • ACE, angiotensin converting enzyme; ARB, angiotensin receptor blockers; CCB, calcium channel blockers; pBV, probability of producing the best value; SUCRAF, surface under the cumulative ranking curve (calculated in frequentist setting).