Table 1

Schedule of enrolment, intervention and assessment

Timepoint	Study period
	Enrolment	Allocation	Postallocation
	At arrival	After evaluation	During treatment	24 hours after treatment	7 days after treatment	Discharge	30 days after treatment	90 days after treatment
Enrolment
Eligibility screen	X
Informed consent	X
Allocation		X
Interventions
GA			X
CS			X
Assessments
Baseline variables	X	X
Brain image	X			X
mRS						X	X
NIHSS	X			X	X		X	X
mTICI			X
All-cause mortality								X
Length of stay								X
ICU stay and length								X
Converting rate			X
Adverse event			X					X

CS, conscious sedation; GA, general anaesthesia; ICU, intensive care unit; mRS, modified Rankin Score; mTICI, modified Thrombolysis in Cerebral Infarction; NIHSS, National Institute of Health Stroke Scale.