Table 3

Screening characteristics of the total study population

Included
(n=297)
Excluded
(n=109)
P value
(t-test)
Age (years)66.5 (7.1)68.1 (7.7)0.061
Female (%)230 (77)80 (71)0.013
BMI (kg/m2)28.1 (5.3)26.4 (4.4)0.003
Adapted KOOS*
 Stiffness38.5 (21.6)24.3 (18.5)<0.001
 Pain31.3 (19.7)17.7 (14.6)<0.001
 Function32.9 (19.1)19.6 (16.3)<0.001
 Total33.1 (18.8)19.6 (15.4)<0.001
NRS pain last week (0–10)
 Index knee4.6 (2.8)2.6 (2.2)<0.001
 Contralateral knee2.8 (2.5)1.6 (2.2)<0.001
KIDA
 Mean JSW index knee (mm)5.5 (1.0)5.5 (1.1)0.700
 Minimum JSW index knee (mm)2.5 (1.3)2.1 (1.0)0.001
KL grade (%)NDNA
 Grade 051 (17)







 Grade 190 (30)
 Grade 288 (30)
 Grade 354 (18)
 Grade 410 (3)
  • Continuous variables are given as mean values, SD between brackets and categorical variables as total number, percentages between brackets. Differences between included and excluded patients were evaluated using t-tests and Χ2 test (gender).

  • *A number of KOOS questions was used, weighted to provide a score for stiffness, pain and function of 0 (most severe) to 100 (no limitations).

  • BMI, body mass index; JSW, joint space width; KIDA, knee image digital analysis; KL, Kellgren and Lawrence; KOOS, Knee injury and Osteoarthritis Outcome Score; NA, not applicable; ND, not determined; NRS, Numeric Rating Scale.