Table 3

Association between latent multimorbidity membership and outcomes in individuals aged 50–64 and ≥65 years

Variables*Aged 50–64 yearsAged ≥65 years
‘Cardio-metabolic’ class‘Respiratory-mental-articular’ class‘Cardio-metabolic’ class‘Respiratory-mental-articular’ class
Loneliness (yes/no)1.8 (1.7 to 2.0)2.5 (2.0 to 3.0)1.3 (1.2 to 1.5)1.9 (1.7 to 2.3)
Ever smoked (yes/no)1.1 (1.0 to 1.2)1.5 (1.2 to 1.7)1.0 (0.9 to 1.0)1.8 (1.5 to 2.0)
Physical activity (yes/no)0.4 (0.4 to 0.5)0.5 (0.5 to 0.6)0.5 (0.5 to 0.6)0.4 (0.4 to 0.5)
Limitations in ADL (yes/no)3.2 (2.9 to 3.6)3.9 (3.3 to 4.7)2.3 (2.1 to 2.5)4.0 (3.5 to 4.6)
Self-rated health
 Good1111
 Moderate4.8 (4.3 to 5.2)3.9 (3.2 to 4.7)3.1 (2.9 to 3.4)5.7 (4.8 to 6.8)
 Poor12.8 (11.3 to 14.4)12.9 (10.5 to 16.0)6.2 (5.6 to 6.9)19.4 (16.2 to 23.4)
 Memory: Immediate recall0.9 (0.9 to 0.9)0.9 (0.9 to 1.0)0.9 (0.9 to 0.9)0.9 (0.9 to 1.0)
 Memory: Delayed recall0.9 (0.9 to 0.9)0.9 (0.9 to 1.0)0.9 (0.9 to 0.9)0.9 (0.9 to 1.0)
 Verbal fluency1.0 (1.0 to 1.0)1.0 (1.0 to 1.0)0.9 (0.9 to 1.0)1.0 (1.0 to 1.0)
  • The reference group for the multimorbidity group variable was the ‘healthy’ class.

  • Relative risk ratios (95% CI) from multinomial logistic regression models.

  • Models were run in 100 imputed datasets and results combined using Rubin’s rules.

  • *Adjusted for sex, age, marital status, education level, wealth and region.

  • ADL, activities of daily living.