Table 1

Outline of statistical plan

ObjectivesOutcomesOutcome measureCovariatesAnalysis
Primary objective
 What is the prevalence of HIV?HIV infection (yes/no)Self-reported HIV positive status or a positive HIV test result*SociodemographicDescriptive statistics: n (%) 95% CI or mean (SD) or median (IQR) per categorical covariate
 What behaviours are associated with HIV transmission?HIV infection (yes/no)Self-reported HIV positive status or a positive HIV test result*Sociodemographic
†Sexual behavioural
‡Substance use
GLMM with binary logistic distribution
 What factors are associated with testing behaviours for HIV?HIV testing ever done (yes/no)
HIV testing done in past 6 months (yes/no)
Self-reported response to HIV testing*Sociodemographic
† Sexual behavioural
‡ Substance use
§Access and use of health services
¶HIV-related healthcare
GLMM with binary logistic distribution
 What are the levels of knowledge regarding HIV transmission and acquisition?HIV knowledge** (adequate/ inadequate)Self-reported responses to HIV knowledge questions*SociodemographicDescriptive statistics: n (%) 95% CI or mean (SD) or median (IQR) per categorical covariate
 What are the key individual and structural factors that affect vulnerability to HIV?HIV vulnerability** (high/low)Combination of knowledge and behavioural practices indicative of high vulnerability*Sociodemographic
† Sexual behavioural
‡ Substance use
§Access and use of health services
¶HIV-related healthcare
GLMM with binary logistic distribution
Secondary Objectives
 What is the incidence of HIV?HIV infection within the last 6 months (yes/no)A positive HIV test result with infection within the last 6 months, using detuned assays*SociodemographicDescriptive statistics: n (%) 95% CI or mean (SD) or median (IQR per categorical covariate
 What are the levels of access to and use of health services?Access and use of health services** (adequate/ inadequate)Self-reported responses to access and use of health services
Resources use metrics from administrative databases
*SociodemographicDescriptive statistics: n (%) 95% CI or mean (SD) or median (IQR per categorical covariate
  • *Sociodemographic: age group (ordinal), residence (categorical), ethno-racial identity (categorical), income (categorical), gender/sex (categorical), migration (categorical), marital status (categorical), education (ordinal), religion (categorical), employment (categorical), housing (ordinal).

  • †Sexual behavioural: age at first intercourse (continuous), sexual orientation (categorical), sexual practices (categorical), number of partners (count), condom use (ordinal), partners HIV status (categorical), transactional sex (categorical), substance use and sex (categorical), genital cutting (categorical).

  • ‡Substance use: injection drug use (categorical) and other substances (categorical).

  • §Access and use of health services: self-rated health (ordinal), primary care provider (categorical), service use (categorical), difficulties in access (categorical), sources of health information (ordinal), condom procurement (categorical), immunisation (categorical), sexually transmitted infection testing (categorical).

  • ¶HIV-related healthcare: ever tested (categorical), self-reported status (categorical), access to care (ordinal), access to medication (ordinal), alternative medicines (categorical), HIV testing practices (ordinal), HIV knowledge (ordinal).

  • **Outcome measures will be categorised after deliberation with A/C study investigators.

  • A/C, African/Caribbean; GLMM, generalised linear mixed models; n, sample size.