Table 1

Index tests and input parameters that will be tested for use in the three logistic regression models

TestResultInput parameters that will be tested for use in the three logistic regression models (result or unit)
Relevant demographicsAge in yearsAge (years)
Physical examination of abdomenBladder palpable/not palpableN/A
Digital rectal examinationProstate mild/moderate/severe enlargement
Further assessment for prostate cancer required/not required
Prostate size (enlarged/not enlarged)
Prostate Specfic Antigen (PSA)PSA value—established thresholds for further assessment for prostate cancer (typically >3 ng/mL) or benign enlargement (typically ≥1.5 ng/mL).
For clinical decision support tool: continuous variable in ng/mL
PSA (ng/mL)
International Consultation on Incontinence Questionnaire Male Lower Urinary Tract Symptoms Short FormTotal score (0–52), voiding symptom score (0–20), storage symptom score (0–24). Individual symptom bother scores scored separately from symptom severity scores (0–130)Storage/incontinence symptoms subscore
Voiding symptoms subscore
International Prostate Symptom Score questionnairesTotal score (0–35)Storage/incontinence symptoms subscore
Voiding symptoms subscore
Bladder diaryWaking (day) time frequency, sleeping (night) time frequency, 24 hours voided volume, daytime voided volume, nocturnal voided volume, average volume voided each void, total urgency scoresMean urgency score
Mean 24 hours fluid intake (mL)
Uroflowmetry (Flowtaker)Maximum flow rate, voided volume against normal age-adjusted range. Single value in mL/sMedian maximum flow rate (mL/s)
Median voided volume (mL)
Mean 24 hours frequency
Mean nocturia
Post void residualResidual volume against normal age-adjusted range. Single value in mLPost void residual volume (mL)
  • PSA, prostate-specific antigen.