Underlying causes of death grouped by specific individual causes or related groups of causes, where cause of death is known
| Causes | Participants with Down syndrome (n=57) | Participants without Down syndrome (n=205) |
| Aspiration/reflux/choking | <5 | 22 (10.8%) |
| Respiratory infection | <5 | 21 (10.3%) |
| Down syndrome | 21 (36.8%) | <5 |
| Other malignancy | <5 | 19 (9.3%) |
| Other condition | <5 | 17 (8.3%) |
| Epilepsies | <5 | 13 (6.4%) |
| Acute myocardial infarction | <5 | 13 (6.4%) |
| Gastrointestinal malignancy | <5 | 12 (5.9%) |
| Stroke | <5 | 11 (5.4%) |
| Other cardiovascular disease | <5 | 11 (5.4%) |
| Other respiratory condition | <5 | 9 (4.4%) |
| Other infection | 5 (8.8%) | 6 (2.9%) |
| Cerebral palsy | <5 | 11 (5.4%) |
| Dementia | 9 (15.8%) | <5 |
| Other gastrointestinal disorders | <5 | 8 (3.9%) |
| Ulcer/gastrointestinal perforation | <5 | 7 (3.4%) |
| Diabetes | <5 | 7 (3.4%) |
| Other congenital condition | <5 | 6 (2.9%) |
| Other ischaemic heart condition | <5 | 6 (2.9) |
| Mental health | <5 | <5 |
| Other neurological conditions | <5 | <5 |
| Renal failure | <5 | <5 |
| All deaths | 57 (100%) | 205 (100%) |