Table 5

Clinical outcomes (HoNOS)

Implementation siteComparator site
BaselineYear 1Year 2P valueP valueBaselineYear 1Year 2P valueP value
(n=52)(n=77)(n=53)Y1 vs baselineY2 vs baseline(n=28)(n=16)(n=11)Y1 vs baselineY2 vs baseline
Change in HoNOS scores (from referral to 1 year)
1. Overactive, aggressive, disruptive or agitated behaviour−0.56 (1.73)−0.43 (1.72)−0.69 (1.45)0.590.78−0.43 (1.55)−1.06 (1.65)−0.09 (1.14)**
2. Non-accidental self injury−0.50 (1.38)−0.22 (1.26)−0.22 (1.15)0.180.21−0.25 (0.84)−0.06 (1.29)−0.36 (1.43)**
3. Problem drinking or drug taking−0.40 (1.48)−0.15 (1.87)0.04 (1.71)0.300.120.14 (1.04)−0.31 (1.20)−0.10 (1.52)**
4. Cognitive problems−0.27 (1.34)−0.15 (1.32)−0.06 (1.32)0.480.33−0.29 (1.18)−0.38 (0.96)−0.50 (1.51)**
5. Physical illness or disability problems−0.23 (1.10)0.03 (1.35)0.02 (1.08)0.190.170.11 (0.50)−0.38 (1.02)0.45 (1.44)**
6. Problems associated with hallucinations and delusions−0.56 (1.62)−0.71 (1.70)−0.11 (1.51)0.740.14−0.86 (1.46)−1.81 (1.42)−0.91 (1.76)**
7. Problems with depressed mood−0.50 (1.59)−0.19 (1.49)−0.55 (1.12)0.240.94−0.46 (1.29)−0.88 (1.41)−0.55 (1.21)**
8. Other mental and behavioural problems−0.45 (1.53)−0.73 (1.81)−0.27 (1.49)0.580.68−0.61 (1.26)−0.75 (1.98)−0.36 (1.69)**
9. Problems with relationships−0.83 (1.32)−0.41 (1.51)−0.20 (1.25)0.070.013−0.21 (1.26)−1.00 (1.41)−0.10 (0.57)**
10. Problems with activities of daily living−0.33 (1.57)−0.32 (1.55)−0.46 (1.47)0.850.68−0.64 (1.16)−1.00 (1.55)0.18 (0.75)**
11. Problems with living conditions−0.20 (1.51)−0.33 (1.44)0.08 (1.21)0.690.28−0.36 (1.31)−0.69 (1.20)0.45 (1.13)**
12. Problems with occupation and activities−0.33 (1.64)−0.19 (1.47)0.30 (1.45)0.540.037−0.25 (1.58)−1.06 (1.57)−0.09 (1.45)**
  • Mean (SD) change in HoNOS scores from referral to 1 year at each trust for patients accepted onto EIP pathway. Excludes EIP to EIP transfers. P values from paired t-tests.

  • *P values not calculated due to amount of missing data.

  • EIP, early intervention in psychosis; HoNOS, Health of the Nation Outcome Scales.