Clinical stage, developmental trajectories, and at-risk mental states in the Optymise cohort at baseline
| N | Percentage of sample | |
| Clinical stage | ||
| Stage 1a | 804 | 29.1% |
| Stage 1b | 1625 | 58.7% |
| Stage 2+ | 338 | 12.2% |
| Proposed pathophysiological mechanism | ||
| Hyperarousal-anxious depression | 2024 | 73.2% |
| Neurodevelopmental-psychosis | 346 | 12.5% |
| Circadian-bipolar spectrum | 303 | 11.0% |
| No mood syndrome | 94 | 3.4% |
| At-risk mental states | ||
| Psychosis-like experiences | 599 | 21.7% |
| Mania-like experiences | 460 | 16.6% |
| Circadian disturbance | 410 | 14.8% |