Table 2

Clinical stage, developmental trajectories, and at-risk mental states in the Optymise cohort at baseline

NPercentage of sample
Clinical stage
 Stage 1a80429.1%
 Stage 1b162558.7%
 Stage 2+33812.2%
Proposed pathophysiological mechanism
 Hyperarousal-anxious depression202473.2%
 Neurodevelopmental-psychosis34612.5%
 Circadian-bipolar spectrum30311.0%
 No mood syndrome943.4%
At-risk mental states
 Psychosis-like experiences59921.7%
 Mania-like experiences46016.6%
 Circadian disturbance41014.8%