Table 2B

Sample size estimation for the diagnostic impact outcome one antibiotic arm to standard of care arm (pairwise comparison)

Power (X2 difference between independent proportions)Effect size (50% SoC vs 60% amoxycillin or azithromycin)Effective sample per arm (sputum negative participants needed)
  • Highlighted entries indicates target power and respective sample size estimates based on knowledge of TB risk, ability to produce and submit sputum, and loss to follow-up.

  • Stata code: power two proportions 0.5 and 0.6, test (χ2), power (0.80), n ratio (1).

  • SoC, standard of care; TB, tuberculosis.