Table 2

Relative mortality burden of hospital admission by disease grouping and improvements in hospitalisation incidence and survival

ICD-10Disease groupingDisease importanceAverage 10-year improvements
HR (95% CI)
Survival to incidence
ratio (SE)
Total hospital visits5-Year mortality (HR)Relative weightIncidenceSurvivalCombined
J09–J18Influenza and pneumonia110 9855.280.0681.19 (1.11 to 1.27)0.86 (0.80 to 0.92)1.02 (0.92 to 1.12)0.47 (0.13)
R00–R09Symptoms and signs involving the circulatory and respiratory systems225 5042.080.0610.88 (0.85 to 0.92)0.79 (0.73 to 0.86)0.70 (0.64 to 0.76)0.65 (0.14)
C30–C39Malignant neoplasm of respiratory and intrathoracic organs54 17821.120.0610.83 (0.75 to 0.91)0.81 (0.74 to 0.89)0.67 (0.59 to 0.77)0.52 (0.15)
R10–R19Symptoms and signs involving the digestive system and abdomen174 0552.560.0600.87 (0.83 to 0.91)0.89 (0.82 to 0.97)0.77 (0.70 to 0.85)0.45 (0.19)
R50–R69General symptoms and signs157 3572.670.0570.90 (0.85 to 0.94)0.97 (0.93 to 1.02)0.87 (0.81 to 0.94)0.19 (0.19)
C15–C26Malignant neoplasms of digestive organs71 9818.130.0560.79 (0.73 to 0.85)0.67 (0.63 to 0.72)0.53 (0.48 to 0.59)0.63 (0.08)
I30–I52Other forms of heart disease142 8982.700.0520.78 (0.74 to 0.83)0.84 (0.80 to 0.87)0.66 (0.61 to 0.70)0.43 (0.06)
C76–C80Malignant neoplasms of ill defined, secondary and unspecified sites39 33926.130.0470.84 (0.76 to 0.93)0.69 (0.61 to 0.79)0.58 (0.49 to 0.69)0.68 (0.16)
Z40–Z54Persons encountering health services for specific procedures and healthcare157 8412.150.0441.00 (0.95 to 1.05)0.74 (0.69 to 0.80)0.74 (0.68 to 0.81)1.00 (0.19)
I60–I69Cerebrovascular diseases100 9073.060.0420.79 (0.74 to 0.85)0.82 (0.76 to 0.87)0.65 (0.59 to 0.71)0.46 (0.09)
K55–K63Other diseases of intestines206 1781.720.0410.94 (0.91 to 0.98)0.80 (0.77 to 0.84)0.76 (0.71 to 0.80)0.80 (0.12)
J40–J47Chronic lower respiratory diseases78 4673.990.0400.78 (0.73 to 0.84)0.79 (0.72 to 0.86)0.62 (0.55 to 0.69)0.49 (0.11)
I20–I25Ischaemic heart diseases175 6051.830.0390.65 (0.63 to 0.68)0.77 (0.72 to 0.82)0.50 (0.46 to 0.55)0.38 (0.05)
N30–N39Other diseases of the urinary system126 3292.310.0391.04 (0.99 to 1.10)1.24 (1.15 to 1.34)1.29 (1.17 to 1.42)0.84 (0.22)
K20–K31Diseases of oesophagus, stomach and duodenum172 2061.830.0380.72 (0.69 to 0.75)0.88 (0.79 to 0.96)0.63 (0.56 to 0.70)0.29 (0.11)
J20–J22Other acute lower respiratory infections77 5203.570.0361.11 (1.03 to 1.20)1.11 (1.06 to 1.17)1.24 (1.13 to 1.36)0.50 (0.15)
S70–S79Injuries to the hip and thigh78 2312.640.0280.87 (0.78 to 0.96)1.02 (0.98 to 1.06)0.89 (0.79 to 0.99)0.12 (0.14)
A30–A49Other bacterial diseases33 6136.600.0231.56 (1.39 to 1.74)0.94 (0.77 to 1.15)1.46 (1.16 to 1.84)0.13 (0.21)
T80–T88Complications of surgical and medical care, not elsewhere classified75 2172.320.0231.04 (0.97 to 1.11)0.83 (0.74 to 0.94)0.86 (0.75 to 0.99)0.84 (0.40)
N17–N19Renal failure37 2135.140.0221.02 (0.91 to 1.15)0.82 (0.73 to 0.91)0.83 (0.71 to 0.98)0.90 (0.42)
I80–I89Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified84 0731.940.0210.80 (0.75 to 0.85)0.79 (0.72 to 0.86)0.63 (0.56 to 0.71)0.52 (0.12)
K90–K93Other diseases of the digestive system47 0912.980.0190.98 (0.90 to 1.07)0.83 (0.72 to 0.95)0.82 (0.69 to 0.96)0.91 (0.50)
I70–I79Diseases of arteries, arterioles and capillaries47 4102.950.0190.67 (0.61 to 0.74)0.91 (0.85 to 0.99)0.61 (0.54 to 0.69)0.19 (0.08)
K50–K52Non infective enteritis and colitis59 1832.270.0180.73 (0.68 to 0.79)0.89 (0.84 to 0.95)0.65 (0.59 to 0.72)0.27 (0.08)
S00–S09Injuries to the head64 9252.090.0180.95 (0.88 to 1.02)0.98 (0.90 to 1.08)0.93 (0.82 to 1.05)0.22 (0.72)
C50–C50Malignant neoplasm of breast39 3583.210.0170.81 (0.74 to 0.89)0.31 (0.27 to 0.36)0.25 (0.21 to 0.30)0.85 (0.07)
C60–C63Malignant neoplasms of male genital organs22 3123.230.0100.91 (0.79 to 1.05)0.50 (0.44 to 0.57)0.45 (0.37 to 0.55)0.88 (0.14)
G30–G32Other degenerative diseases of the central nervous system46553.290.0020.75 (0.51 to 1.10)0.96 (0.73 to 1.28)0.78 (0.49 to 1.24)0.11 (0.44)
Total2 664 6312.771.0000.89 (0.88 to 0.90)0.83 (0.76 to 0.90)0.74 (0.72 to 0.75)0.61 (0.16)
  • ICD-10: diseases contained within the disease grouping, coded by ICD-10. See online supplementary file 4 for counts of 3-letter ICD-10 records within each ICD-10 block. Total hospital visits: number of first-time admissions with main diagnosis falling within the disease block. 5-year mortality: mortality within the first 5 years after admission compared with individuals who had not yet or ever been admitted for the disease group. Relative weight: relative burden of death as a function of hospital admissions and 5-year mortality, scaled to [0–1]. Incidence: average HR of being admitted to hospital for each subsequent decade of birth. Survival: all-cause mortality HR after being admitted for the disease in 2011 compared with 2001. Combined: linear combination of changes in disease incidence and survival. 95% CIs are listed in parentheses. Ratio: the ratio of absolute changes in disease survival to incidence of hospital admission, measured on log HR scale. SE is listed in parentheses. See online supplementary file 12 for these data by sex and deprivation. See online supplementary file 8 for the relative burdens of all disease groupings with more than 15 000 first-time hospital admissions.

  • ICD-10, International Classification of Disease Codes, Tenth Revision.