Commonly prescribed grapefruit—affected drugs and possible adverse events*
| Amiodarone | Torsades de pointes |
| Apixaban | Gastrointestinal bleeding |
| Atorvastatin | Myopathy, rhabdomyolysis |
| Budesonide (oral) | Hyperglycaemia, Cushingoid features |
| Buprenorphine (buccal) | Torsades de pointes, respiratory depression |
| Buspirone | Sedation, psychomotor impairment |
| Clopidogrel | Lack of efficacy |
| Cyclophosphamide | Lack of efficacy |
| Cyclosporine | Nephrotoxicity, excessive immunosuppression |
| Dextromethorphan | Dizziness, somnolence, anxiety, hallucinations |
| Domperidone | Torsades de pointes |
| Dronedarone | Torsades de pointes |
| Felodipine | Headache, peripheral oedema, hypotension |
| Fentanyl (sublingual) | Sedation, respiratory depression |
| Ketamine (oral) | Hallucinations, loss of coordination and motor skills |
| Loperamide | Drowsiness, respiratory depression |
| Lovastatin | Myopathy, rhabdomyolysis |
| Lurasidone | Torsades de pointes |
| Methadone | Sedation, respiratory depression |
| Methylprednisolone (oral) | Hyperglycaemia, Cushingoid features |
| Nifedipine | Headache, peripheral oedema, hypotension |
| Oxycodone | Sedation, respiratory depression |
| Quetiapine | Dizziness, somnolence, hypotension |
| Rivaroxaban | Gastrointestinal bleeding |
| Silodosin | Dizziness, weakness, syncope |
| Simvastatin | Myopathy, rhabdomyolysis |
| Solifenacin | Torsades de pointes |
| Tacrolimus | Torsades de pointes, nephrotoxicity, neurotoxicity |
| Tamsulosin | Orthostatic hypotension |
| Ticagrelor | Gastrointestinal bleeding |
| Triazolam | Excessive drowsiness, sedation |
| Verapamil | Arrhythmias (heart block, bradycardia), hypotension |
| Ziprasidone | Torsades de pointes, orthostatic hypotension |
*Adapted from Bailey.19