Authors | Participants/n/age/gender | Timing of intervention | Number and type of studies included in review | Method of data synthesis (narrative/meta-analysis) |
Biagioli et al19 | Infants/n=167/<5 weeks/males 45.5%, 44.4%, 49.4% | 7 days | 4 RCTs | Meta-analysis |
Gordon et al18 | Infants/n=1121/2–16 weeks/balanced numbers of boys and girls | 4–21 days | 1 RCT | Narrative |
Hall et al34 | Infants/n=309 (27/32 and 83/92 and 199/267)/2–8 weeks/gender not reported | Not reported | 3 RCTs | Narrative |
Salvatore et al29 | 1 consensus review, 1 review, 1 SR | NA | NA | Narrative |
Xu et al58 | Infants/n=423/3–6 months | L.reuteri. 21 and 28 days | 6 RCTs | Meta-analysis |
Urbańska and Szajewska59 | Infants/n=838/birth to 26 weeks | L.reuteri. Up to 1 month for management group and up to 3 months for the prevention group | 5 RCTs | Meta-analysis |
NA, not available; RCT, randomised controlled trial; SR, systematic review.