Table 1

Data collection and source of data

DataSourcePreinterventionIntervention3-month follow-up*
Sociodemographic data: age, sex, residence (before and after discharge), education and ethnicityProgress notes.××
Medications at admission, discharge and 3 months after dischargeBPMH; DBI report; number of medications from participant chart; DIS† via HDNS.×××
Frailty status prior to admission, CFS12Progress notes (if CFS score not provided in progress notes assessment will be made by research team using information in progress notes).××
Comorbidities at admission: number and Charlson comorbidity index37ICD-10 codes; progress notes based on medical history taken on admission with all active medical conditions counted.××
Reason for admissionProgress notes.× ×
Falls in past year prior to admissionParticipant/family.×
Falls during admissionProgress notes.‡××
Falls risk and pressure ulcer risk assessmentParticipant chart.××
In-hospital new adverse drug reactions (assessed using the Naranjo criteria38 independently by at least two research team members)Progress notes.‡××
Length of hospitalisationProgress notes.××
In-hospital pressure ulcersProgress notes.‡××
Patients attitudes towards deprescribing at recruitmentrPATD questionnaire39 self-completed at recruitment.×
Adverse drug withdrawal events during hospitalization as defined by Graves et al40Progress notes.‡×
Quality of life at admissionEQ-5D5L or proxy version.41×
Cognition at admission, MoCA42Progress notes or interview.×
Emergency department visits and readmission to hospitalElectronic medical records.×
MortalityVital statistics via HDNS.×
  • *3-month follow-up data for both intervention and control groups will be extracted when it becomes available from HDNS; the data are not available in real time.

  • †The Nova Scotia DIS is a province-wide system that contains a comprehensive medication profile for everyone who gets a prescription filled in a community pharmacy in Nova Scotia. Accuracy of the DIS at 3 months after discharge will be validated with a follow-up phone call to 10% of participants (randomly chosen) in the intervention group. A random number generator will be used in Excel to create a number for all participants. The data will then be sorted according to the random numbers and the top 10% of participants on the newly sorted list will be selected for each unit. The DIS is accessed via approval from HDNS.

  • ‡Passive surveillance was used for these outcomes. Progress notes were reviewed in full after discharge to identify these outcomes including whether they were specifically noted as such by the care team (eg, adverse drug reactions).

  • BPMH, Best Possible Medication History; CFS, Clinical Frailty Scale; DBI, Drug Burden Index; DIS, Drug Information System; EQ-5D-5L, EuroQol-5 dimension-5 level; HDNS, Health Data Nova Scotia; ICD-10, International Classification of Diseases-Tenth Revision; MoCA, Montreal Cognitive Assessment; rPATD, Revised Patients’ Attitudes Toward Deprescribing.