Table 1

Number of cases and controls for ulcerative colitis and Crohn’s disease, with ORs for exposure and the corresponding 95%CI.

Exposed to quartz during the 5 years before diagnosis in 2007–2016
Ulcerative colitisCrohn’s disease
Cases (n)Controls (n)OR95% CICases (n)Controls (n)OR95% CI
Total
 Unexposed18 41137 11619 67219 2931
 Exposed1 4192 544 1.13* 1.06 to 1.21 5891 2290.950.86 to 1.06
Duration of exposure
 0 years18 41137 11619 67219 2931
 ≤ 1 year3185961.080.94 to 1.241222960.820.66 to 1.01
 1.01 to 5 years3777171.070.94 to 1.211723630.940.78 to 1.13
 5.01 to 10 years485828 1.19 1.06 to 1.331 1994020.990.83 to 1.17
 > 10 years239403 1.21 1.02 to 1.42 961681.140.89 to 1.48
Cumulative exposure (mg/m3)
 018 41137 11619 67219 2931
 0.01 to 0.991 2832 347 1.11 1.03 to 1.19 5251 1200.930.84 to 1.04
 ≥ 1.0136197 1.40 1.12 to 1.74 641091.170.86 to 1.60
Men
 Unexposed8 45917 17214 0958 0911
 Exposed1 2382 220 1.33 1.05 to 1.22 4801 0590.890.80 to 1.00
Duration of exposure
 0 years8 45917 17214 0958 0911
 ≤ 1 year2615051.040.90 to 1.22902450.720.56 to 0.92
 1.01 to 5 years3186131.050.92 to 1.211433010.930.76 to 1.15
 5.01 to 10 years441738 1.21 1.08 to 1.37 1643580.900.75 to 1.09
 > 10 years218364 1.22 1.03 to 1.46 731551.060.81 to 1.39
Cumulative exposure (mg/m3)
 08 45917 17214 0958 0911
 0.01 to 0.991 1312 057 1.12 1.03 to 1.21 4349780.870.78 to 0.99
 ≥ 1.0107163 1.34 1.05 to 1.71 46811.120.78 to 1.62
Women
 Unexposed9 95219 94415 57711 2021
 Exposed1813241.120.93 to 1.34109170 1.29 1.01 to 1.65
Duration of exposure
 0 years9 95219 94415 57711 2021
 ≤ 1 year57911.250.90 to 1.7532511.250.81 to 1.96
 1.01 to 5 years591041.140.83 to 1.5629620.940.60 to 1.46
 5.01 to 10 years44900.980.68 to 1.413544 1.62 1.03 to 2.54
 > 10 years21391.080.63 to 1.8313132.020.93 to 4.36
Cumulative exposure (mg/m3)
 09 95219 94415 57711 2021
 0.01 to 0.991522901.050.86 to 1.29911421.290.99 to 1.68
 ≥1.02934 1.71 1.04 to 2.80 18281.290.72 to 2.34
  • Data for the total study population as well as data stratified into men and women are presented. Both duration of exposure in years and the cumulative exposure were calculated using the job exposure matrix.

  • * Bold values indicate statistical significanse (p<0.05)