(1) | (2) | (3) | |
QALYs | Total cumulative cost in£s | Net benefit in £s (based on £20 000 per-annum) | |
Panel A: uptake analysis | |||
BL versus FU6 | 0.017 (0.002 to 0.032), p=0.022 | −95.59 (−511.84 to 320.65), p=0.653 | 154.74 (12.56 to 297.22), p=0.033 |
BL versus FU12 | 0.030 (0.005 to 0.054), p=0.019 | −283.42 (−925.50 to 358.66), p=0.387 | 734.27 (66.02 to 1402.53), p=0.031 |
BL versus FU18 | 0.056 (0.017 to 0.094), p=0.004 | −452.56 (−1365.89 to 460.74), p=0.331) | 1955.50 (208.50 to 3702.50), p=0.028 |
Panel B: cessation analysis | |||
BL versus FU6 | −0.036 (−0.068 to −0.004), p=0.029 | 689.00 (161.69 to 1216.31), p=0.010 | −624.35 (−1224.21 to −24.50), p=0.041 |
BL versus FU12 | −0.068 (−0.132 to −0.005), p=0.034 | 857.27 (251.68 to 1462.86), p=0.006 | −1653·42 (−2959.04 to −347.79), p=0.013 |
BL versus FU18 | −0.102 (−0.173 to −0.031), p=0.005 | 1335·33 (112.85 to 2557.81), p=0.032 | −3894·42 (−7256.51 to −532.33), p=0.023 |
Variables in the outcome equation: gender, age (in 5-year groups), living arrangements, employment status, education and presence of limiting conditions. Variables in the matching equation: gender, age (in 5-year groups), living arrangements, employment status, education, presence of limiting conditions, satisfied with transport, EQ5D domains scores (not utility value), the ICEpop CAPability measure for Older people (ICECAP-O) score, six questions from the Social Support Inventory, distance to nearest community asset and cost of healthcare services in previous 6 months (before baseline). Net benefit calculations assume a threshold value of £20 000 per annum (hence £10 000 per 6 months and £30 000 for 18 months). In the uptake analysis, BL versus 6 months compares NN (control group) with NY (treatment group). BL versus 12 months compares NNN (control group) with NYY (treatment group). BL versus FU18 compares NNNN (control group) with NYYY (treatment group). In the cessation analysis, BL versus 6 months compares YY (control group) with YN (treatment group). BL versus 12 months compares YYY (control group) with YNN (treatment group). BL versus FU18 compares YYYY (control group) with YNNN (treatment group).
FU6 is the 6-month follow-up.
BL, baseline; FU, follow-up period; QALYs, quality-adjusted life years.