Table 1

Characteristics of all and lead trials across 13 Polish academic medical centres completed between 2009 and 2013

All trialsLead trials
Total305100%75100%
Enrolled participants:
 1–1009832.1%4762.7%
 101–50013644.6%2229.3%
 501–10005016.4%34.0%
 >1000206.6%22.7%
 N/R10.3%11.3%
Study phase
 I62.0%22.7%
 I/II41.3%22.7%
 II7925.9%68.0%
 II/III134.3%45.3%
 III12340.2%*810.7%
 IV4213.8%2634.7%
 N/A3812.5%2735.9%*
Trial status
 Completed24179.0%5472.0%
 Terminated4013.1%45.3%
 Unknown247.9%1722.7%
Trial completion year
 20095317.4%912.0%
 20104916.1%1317.3%
 20115417.7%1722.7%
 20126722.0%1621.3%
 20138226.8%*2026.7%
Trial primary completion year
 <2009196.2%34.0%
 20095518.0%1216.0%
 20104715.4%1418.7%
 20115417.7%1216.0%
 20126822.4%*1621.3%
 20135919.3%1722.7%
 N/R31.0%11.3%
Registration time†
 Before trial start16754.7%*1824.0%
 After trial start10333.8%2837.3%
 After trial completion date3210.5%2736.0%
 After publication31.0%22.7%
Population
 Adult24881.3%5066.7%
 Paediatric5317.4%2533.3%
 Mixed31.0%00.0%
 Unclear10.3%00.0%
Type of intervention
 Behavioural20.7%11.3%
 Biological3110.2%45.3%
 Device258.2%1114.7%
 Dietary supplement123.9%1114.7%
 Drug20968.5%3040.1%*
 Genetic10.3%11.3%
 Other82.6%68.0%
 Procedure144.6%912.0%
 Radiation10.3%11.3%
 N/A or N/R20.7%11.3%
Monocentre/multicentre
 Multicentre24179.0%1520.0%
 Monocentre5618.4%5370.7%
 N/A or N/R82.6%79.3%
Lead sponsor
 Industry22373.1%810.7%
 Public7624.9%6384.0%
 Other62.0%45.3%
Randomisation status
 Non-randomised175.6%912.0%
 Randomised25984.9%6080.0%
 N/A or N/R299.5%68.0%
Masking
 Double blind16754.8%3749.3%
 Open label11236.7%2634.7%
 Single blind237.5%1114.7%
 N/A or N/R31.0%11.3%
  • *The percentage was calculated by subtracting the remaining % values from 100%.

  • †Registration time was calculated using the study_first_submitted_date and start date/completion date/publication date.

  • N/A, not applicable; N/R, not reported.