Table 2

Dissemination of clinical trial results following trial CD for all, lead, paediatric and adult trials

All trialsLead trialsPaediatric trialsAdult trials
Total305100%75100%53100%248100%
Posting summary results 
 No results posted17557.4%6789.3%3260.4%14056.5%
 Results posted12039.3%56.7%2037.7%9939.9%
 Results submitted103.3%34.0%11.9%93.6%
Posting time on ClinicalTrials.gov among trials with results posted
 Before trial completion41.3%00.0%11.9%31.2%
 ≤12 months after CD196.2%11.3%47.5%156.0%
 >12 ≤ 24 months after CD3611.6%*11.3%815.1%2711.0%†
 >24 ≤ 36 months after CD206.6%22.8%‡47.5%166.5%
 >36 ≤ 48 months after CD175.6%11.3%23.8%156.0%
 >48 ≤ 60 months after CD93.0%00.0%11.9%83.2%
 >60 ≤ 72 months after CD62.0%00.0%00.0%62.4%
 >72 months after CD93.0%00.0%00.0%93.6%
Publication found
 Yes21871.5%5776.0%3667.9%18072.6%
 No8728.5%1824.0%1732.1%6827.4%
Where was publication found?
 ClinicalTrials.gov14447.2%3546.7%2445.2%§11948.0%
 PubMed82.6%00.0%11.9%72.8%
 Google Scholar6421.0%2229.3%1120.8%5321.4%
 Web of Science20.7%00.0%00.0%10.4%
Publication time
 Before trial completion206.6%45.3%11.9%187.3%
 ≤24 months after CD10333.8%3546.7%1935.8%8333.5%
 >24 ≤ 36 months after CD5217.0%79.3%815.1%4417.7%
 >36 ≤ 48 months after CD268.5%68.0%35.7%239.3%
 >48 ≤ 60 months after CD82.6%34.0%47.5%41.6%
 >60 ≤ 72 months after CD72.3%22.7%11.9%62.4%
 >72 months after CD20.7%00.0%00.0%20.8%
Pooled dissemination
 Posting summary results within 12 months¶237.5%11.3%59.4%187.3%
 Publishing results within 24 months¶**12340.3%3952.0%2037.7%10140.7%
 Posting and/or publishing results††13143.0%3952.0%2139.6%10843.5%
 Posting and publishing results‡‡154.9%11.3%47.5%114.4%
 Overall dissemination§§24379.7%5776.0%3973.6%20181.0%
  • *The percentage was calculated by subtracting the remaining % values from 39.3%.

  • †The percentage was calculated by subtracting the remaining % values from 39.9%.

  • ‡The percentage was calculated by subtracting the remaining % values from 6.7%

  • §The percentage was calculated by subtracting the remaining % values from 67.9%.

  • ¶Study results posted on ClinicalTrials.gov before CD or within 12 months after CD

  • **Study results published as a journal publication before CD or within 24 months after CD.

  • ††Study results posted on ClinicalTrials.gov before CD or within 12 months after CD and/or published as a journal publication before CD or within 24 months after CD.

  • ‡‡Study results posted on ClinicalTrials.gov before CD or within 12 months after CD and published as a journal publication before CD or within 24 months after CD.

  • §§Study results posted and/or published as of 7 February 2019.

  • CD, completion date.