Table 1

Schedule of study events

Baseline/
enrolment
SurgeryFollow-up post injury or surgery
14 days3 weeks4 weeks6 weeks8 weeks12 weeks24 weeks
Examination by an orthopaedic surgeon
Informed consent for research
Medical history
Medications
Screening pregnancy test
Surgery if necessary
Study drug administration
Serum lithium test
Renal blood test* (only if necessary)
X-rays (only until fracture has healed)
Surveys
Assessment of adverse events†
Study visit with research assistant
  • *Renal blood test only required if 3-week serum lithium blood test measures ≥1.1 mmol/L.

  • †Adverse events occurring after the first dose of lithium and until the 6 week visit will be collected, reported and followed through to resolution, or until the event is assessed as chronic or stable.