Table 3

Phases of data collection and specific measurements in the LiN study

PhaseMeasurements
Assessments during pregnancy Enrolment package, T1 (gwk 8–21), T2 (gwk 22–27), T3 (gwk 28–31), T4 (gwk 32–35), T5 (gwk 36–41)
Enrolment package in pregnancy, first visit to well-baby clinic (range gwk 8–34)
At well-baby clinic
Web from home*
Mothers and fathers: demographic information, somatic and mental health, medication/smoking/alcohol habits (TWEAK), thoughts about unborn child, life stress (PSI-LS), relational experiences (ECR), adverse childhood experiences (ACE)
Mothers only: FFQ*, hair and urine samples
T1 (gwk 8–21)Both parents: pregnancy anxiety concerns (PRAQ-R), depressive symptoms (EPDS), medication/smoking/alcohol habits (TWEAK), thoughts about unborn child
Mothers only: brief FFQ
T2 (gwk 22–27)
Web from home
Both parents: pregnancy anxiety concerns (PRAQ-R), medication/smoking/alcohol habits (TWEAK), depressive symptoms (EPDS), thoughts about unborn child
Mothers only: brief FFQ
T3 (gwk 28–31)
At well-baby clinic
Both parents: pregnancy anxiety concerns (PRAQ-R), medication/smoking/alcohol habits (TWEAK), depressive symptoms (EPDS), thoughts about unborn child
Mothers only: brief FFQ, blood, urine and hair samples
T4 (gwk 32–35)
Web from home
Both parents: pregnancy anxiety concerns (PRAQ-R), medication/smoking/alcohol habits (TWEAK), depressive symptoms (EPDS), thoughts about unborn child
Mothers only: FFQ
T5 (gwk 36–41)
Web from home
Both parents: pregnancy anxiety concerns (PRAQ-R), medication/smoking/alcohol habits (TWEAK), depressive symptoms (EPDS), thoughts about unborn child
Mothers only: brief FFQ
T6 birth Birth weight; gestational age; birth complications
Follow-up
At well-baby clinic
Web from home*
T7 6 weeks, T8 6 months, T9 12 months, T10 18 months
T7 child age 6 weeks
At well-baby clinic
Web from home*
Infant-mother assessment procedure (MABI)
Infants: diurnal rhythm; DNA extracted from saliva, infant hair samples
Mothers: FFQ*, child nutrition and breast feeding*, maternal hair and urine samples
Both parents: depressive symptoms (EPDS)
T8 child age 6 months
At well-baby clinic
Web from home*
Infants: infant development (Bayley Scales, screening test†); infant social withdrawal behaviour (ADBB); hair and blood samples
Mothers: hair, urine and blood samples, FFQ*, child nutrition and breast feeding*
Both parents: PSI, infant-parent interaction, depressive symptoms (EPDS), perceived infant temperament* (Cameron-Rice‡)
T9 child age 12 months
At well-baby clinic
Web from home*
Infants: infant development (Bayley Scales, screening test†), infant social withdrawal behaviour (ADBB), genetic information extracted from saliva, infant hair and blood samples
Mothers: FFQ*, child nutrition and breast feeding*, maternal hair, urine and blood samples
Both parents: PSI, infant-parent interaction, depressive symptoms (EPDS), perceived infant temperament* (Cameron-Rice‡)
T10 child age 18 months
At well-baby clinic
Web from home*
Web from child care centres¶
Infants: infant development (Bayley Scales, full scale§), infant social withdrawal behaviour (ADBB), infant hair and urine samples
Mothers: maternal hair and urine samples
Both parents: PSI, infant-parent interaction, depressive symptoms (EPDS), child social emotional assessment* (ITSEA)
Childcare centre: child social emotional assessment¶ (ITSEA)
  • *Web from home.

  • †Bayley Scales of Infant and Toddler Development, screening test.46

  • ‡Cameron-Rice perceived temperament scale.48

  • §Bayley Scales of Infant and Toddler Development, full scale.46

  • ¶Web from child care centres.

  • ACE, Adverse Childhood Experiences Scale10; ADBB, Alarm Distress Baby Scale47; ECR, Experiences in Close Relationships Scale37; EPDS, Edinburgh Postnatal Depression Scale34; FFQ, Food Frequency Questionnaire43 44; gwk, gestational week; ITSEA, Infant-Toddler Social and Emotional Assessment50; MABI, Mothers’s Assessment of the Behaviour of the Infant45; PRAQ-R, Pregnancy-Related Anxiety Questionnaire-Revised40; PSI, Parenting Stress Index36; PSI-LS, Parenting Stress Index-Life Stress36; TWEAK, Tolerance, Worried, Eye-opener, Amnesia, Cut-down.