Reasons for discontinuing linaclotide
| Austria (n=86) | Switzerland (n=52) | |
| Discontinued patients, n (%) | 20 (23.3) | 17 (32.7) |
| Lack of effectiveness | 13 (15.1) | 5 (9.6) |
| Adverse events | 8 (9.3) | 10 (19.2) |
| Improvement in symptoms | 5 (5.8) | 5 (9.6) |
| Lack of compliance | 1 (1.2) | 0 |
| Excessive drug effect | 0 | 1 (1.9) |
Austria: Seven patients reported two reasons each.
Switzerland: Four patients reported two reasons each.