Table 4

Risk of bias assessment for preclinical studies

Author, Year Random Sequence Generation Allocation Concealment Blinding of Personnel Blinded Outcome Assessment Incomplete Outcomes Addressed Selective Outcome Reporting Conflicts of Interest A Priori Sample Size Calculation Funding
Cooke, 201624 UnclearUnclearUnclearUnclearUnclearUnclearUnclearUnclearHigh Risk
Cooke, 201522 UnclearUnclearUnclearUnclearUnclearUnclearUnclearUnclearHigh Risk
Piasecki, 201523 UnclearUnclearUnclearUnclearUnclearUnclearUnclearUnclearHigh Risk
Piasecki, 201321 UnclearUnclearUnclearUnclearUnclearUnclearUnclearUnclearHigh Risk
Liu, 200320 UnclearUnclearUnclearUnclearLow riskUnclearUnclearUnclearHigh Risk