Construct validity assessment for preclinical studies
| First author, year | Adult used | Animals with advanced stage disease | Animals immune to HSV | Xenograft model used | Used model with a Humanised immune system |
| Cooke, 201624 | Unclear | No | Unclear | No | Unclear |
| Cooke, 201522 | Unclear | No | Unclear | No | Unclear |
| Piasecki, 201523 | Unclear | Unclear | Unclear | No | Unclear |
| Piasecki, 201321 | Unclear | Unclear | Unclear | No | Unclear |
| Liu, 200320 | Unclear | No | Yes | No | Unclear |
HSV, Herpes Simplex Virus.