Subgroup analysis of the crude and adjusted HR (95% CI) of mood disorder for spine fracture according to age and sex
| Characteristic | HR (95% CI) | |||
| Crude* | P value | Adjusted*† | P value | |
| Young men (20–39 years old, n=33 515) | ||||
| Mood disorder | 1.69 (1.11 to 2.57) | 0.014‡ | 1.30 (0.84 to 2.01) | 0.236 |
| Control | 1.00 | 1.00 | ||
| Young women (20–39 years old, n=64 200) | ||||
| Mood disorder | 1.77 (1.29 to 2.43) | <0.001‡ | 1.47 (1.06 to 2.03) | 0.021‡ |
| Control | 1.00 | 1.00 | ||
| Middle-aged men (40–59 years old, n=40 305) | ||||
| Mood disorder | 1.33 (1.07 to 1.67) | 0.012‡ | 1.16 (0.92 to 1.46) | 0.202 |
| Control | 1.00 | 1.00 | ||
| Middle-aged women (40–59 years old, n=78 420) | ||||
| Mood disorder | 1.31 (1.16 to 1.49) | <0.001‡ | 1.14 (1.00 to 1.30) | 0.049‡ |
| Control | 1.00 | 1.00 | ||
| Old men (60+ years old, n=29 185) | ||||
| Mood disorder | 1.43 (1.24 to 1.64) | <0.001‡ | 1.27 (1.10 to 1.47) | 0.001‡ |
| Control | 1.00 | 1.00 | ||
| Old women (60+ years old, n=55 075) | ||||
| Mood disorder | 1.14 (1.07 to 1.22) | <0.001 | 1.03 (0.96 to 1.10) | 0.402 |
| Control | 1.00 | 1.00 | ||
*Stratified the model for age, income, region of residence and osteoporosis.
†Adjusted the model for the Charlson Comorbidity Index and history of Alzheimer’s dementia.
‡Cox proportional hazards regression model; significance at p<0.05.