Table 1

Characteristics of study participants

Non-DEDDEDP valueTotal
n=57n=152n=209
Age, year±SD61.4±15.557.9±15.20.14958.9±15.3
Gender, female (%)48 (84.2)127 (83.6)1.000175 (83.7)
BCVA, logMAR±SD−0.1±0.0−0.1±0.00.513−0.1±0.0
IOP, mm Hg±SD14.6±2.913.8±2.70.06214.0±2.8
Subjective symptoms, yes (%)5 (8.8)152 (100)***<0.001157 (75.1)
J-OSDI, 0–100±SD19.4±16.037.7±22.2***<0.00132.7±29.7
DEQS, 0–100±SD16.0±14.732.7±21.6***<0.00128.1±21.3
TFBUT, s±SD2.5±2.41.5±0.8***<0.0011.7±1.5
CFS, 0–9±SD2.8±2.53.3±2.60.1923.2±2.6
Schirmer I, mm±SD7.2±8.25.7±6.20.1626.1±6.8
MBI, s±SD15.1±8.110.5±6.3***<0.00111.7±7.1
  • P values were determined using the Student’s t-test (two-tailed) for continuous variables and the χ2 test for categorical variables.

  • ***p<0.001.

  • BCVA, best-corrected visual acuity; CFS, corneal fluorescein staining;DED, dry eye disease; DEQS, Dry Eye-Related Quality-of-Life Score; IOP, intraocular pressure; J-OSDI, Japanese version of Ocular Surface Disease Index; MBI, maximum blink interval; TFBUT, tear film breakup time.