Table 2

Clinical outcomes of patients in each grade of LV diastolic dysfunction

e′≥7 group
No of patients with event/No of patients at risk (cumulative 3-year incidence (%))
e′<7 and E/e′≤14 group
No of patients with event/No of patients at risk (cumulative 3-year incidence (%))
e′<7 and E/e′>14 group
No of patients with event/No of patients at risk (cumulative 3-year incidence (%))
VariablesUnadjustedAdjusted
HR
(95% CI)
P valueHR
(95% CI)
P value
A composite of all-cause death and MACEs134/1384 (10.9)225/1295 (18.2)140/578 (21.6)e′≥7ReferenceReference
e′<7 and E/e′≤141.65
(1.36 to 2.00)
<0.0011.24
(1.02 to 1.52)
0.032
e′<7 and E/e′>142.34
(1.93 to 2.85)
<0.0011.57
(1.28 to 1.94)
<0.001
All-cause death101/1384 (7.8)141/1295 (11.1)87/578 (13.8)e′≥7ReferenceReference
e′<7 and E/e′≤141.34
(1.07 to 1.68)
0.0111.07
(0.85 to 1.36)
0.85
e′<7 and E/e′>141.83
(1.46 to 2.31)
<0.0011.42
(1.11 to 1.82)
0.0049
MACEs45/1384 (4.0)108/1295 (9.3)81/578 (12.7)e′≥7ReferenceReference
e′<7 and E/e′≤142.35
(1.72 to 3.27)
<0.0011.54
(1.13 to 2.16)
0.0064
e′<7 and E/e′>144.01
(2.95 to 5.58)
<0.0012.14
(1.55 to 3.02)
<0.001
  • MACE, major adverse cardiac event.