Table 3

Multivariate analyses - Cox proportional hazards model

VariableUnadjusted HR
(95% CI)
P valueAdjusted HR*
(95% CI)
P value
Death(<0.001)†
 Clinical frailty scale3.50 (2.15 to 5.71)<0.0012.88 (1.23 to 6.68)0.014
 EuroQol-VAS0.96 (0.95 to 0.98)<0.0010.96 (0.93 to 0.98)<0.001
 eGFR0.96 (0.95 to 0.98)<0.0010.97 (0.95 to 1.00)0.04
 Haemoglobin0.97 (0.95 to 0.99)<0.0010.97 (0.94 to 0.99)0.02
Nursing home transfer(<0.001)†
 Age1.07 (1.01 to 1.12)<0.011.10 (1.02 to 1.18)0.02
 Gait speed0.10 (0.03 to 0.31)<0.0010.13 (0.03 to 0.57)0.01
 Geriatric depression scale1.55 (1.25 to 1.91)<0.0011.39 (1.07 to 1.82)0.01
 Dementia diagnosis5.75 (2.99 to 11.06)<0.0014.61 (1.86 to 11.44)0.001
Hospital admission(<0.001)†
 Clinical frailty scale2.04 (1.54 to 2.71)<0.0011.75 (1.21 to 2.51)0.003
 EuroQol-VAS0.97 (0.96 to 0.99)<0.0010.98 (0.96 to 0.99)0.004
  • *Adjusted for age, sex, multiple comorbidities, number of drugs and variables in final model.

  • †P for overall model.

  • eGFR, estimated glomerular filtration rate; VAS, Visual Analogue Scale.