Table 1

Dose titration regimen for the investigational product

Day 1Day 2Day 3Day 4Day 5Day 6Day 7
Week 1 <4 mg THC
50 mg CBD
<6 mg THC
75 mg CBD
<8 mg THC
100 mg CBD
<10 mg THC
125 mg CBD
<12 mg THC
150 mg CBD
<14 mg THC
175 mg CBD
<16 mg THC
200 mg CBD
Morning:Embedded Image
Night:Embedded Image
Morning:Embedded Image
Noon:Embedded Image
Night:Embedded Image
morning:Embedded Image
Noon:Embedded Image
Night: Embedded Imagex2
Morning:Embedded Image
Noon: Embedded Imagex2
MorningEmbedded Image
Noon: Embedded Imagex3
Morning:Embedded Image
Noon: Embedded Imagex4
Morning:Embedded Image
Noon: Embedded Imagex5
Day 8Day 9Day 10Day 11Day 12Day 13Day 14
Week 2 <18 mg THC
225 mg CBD
<20 mg THC
250 mg CBD
<22mgTHC
275 mg CBD
<24 mg THC 300 mg CBD <26 mg THC
325 mg CBD
<28 mg THC
350 mg CBD
Embedded Image <30 mg THC
375 mg CBD
Morning:Embedded Imagex5Morning: Embedded Imagex6Morning:Embedded Imagex7Morning: Embedded Imagex8Morning: Embedded Imagex8Morning:Embedded Imagex8Morning: Embedded Imagex8
  • Embedded Image25 mg CBD and <2 mg THC in a capsule.

  • CBD, cannabidiol; TCH, delta-9-tetrahydrocannabinol .