Definitions of change impact and case complexity: operational definitions of major and minor changes in diagnostic or treatment plan
| Diagnostic plan | Treatment plan | Remarks | |
| Minor | Additional more-detailed MRI or CT thorax of the area already imaged | Logistic change | |
| Major | Additional MRI or CT thorax in a different area from the area already imaged | Change in modality: adding or deleting a therapeutic modality; surgery radiotherapy or chemotherapy | |
| Criterion | Addition of diagnostic plan in a different area than already investigated | Adding or deleting a treatment modality from the treatment plan in the proposed or in a different area | After the major/minor decision is made, the decision registered in the research form will be verified by both specialists (giver and receiver) |