Table 6

C-statistic of each biomarker and optimal sensitivity and specificity using the Youden index

BiomarkerC-statistic (95% CI)SensitivitySpecificityCut-off
NR20.50 (0.42 to 0.58)0.180.850.13 ng/mL
NR2Ab0.45 (0.37 to 0.53)0.050.964.45 ng/mL
PARK70.46 (0.38 to 0.54)0.640.3915.23 ng/mL
NDKA0.53 (0.45 to 0.61)0.370.7574.90 pg/mL
UFD10.49 (0.40 to 0.57)0.240.78313.50 pg/mL
B-FABP0.50 (0.42 to 0.58)0.060.960.22 ng/mL
H-FABP0.58 (0.50 to 0.66)0.350.6519.15 ng/mL
  • NR2Ab, NR2 antibodies.