Table 3

Reasons for refusing to participate in the trial by cluster membership (n=106)

Refusal reasonOverall (%)Cluster 1 (%)Cluster 2 (%)Cluster 3 (%)P value
Lack of interest353535350.99
Treatment preference212612210.52
Caregiver resistance131912100.48
Preferred surgeon to select8012120.13
Fear of research810690.90
Overwhelmed810690.90
Fear of side effects30180<0.01
LAR refused331200.04
In other studies20030.43
Follow-up burden10020.66
  • LAR, legally authorised representative.