Table 1

Schedule of events for this prospective cohort study

ED presentation and initiation of mechanical ventilationAdmit to ICUICU
day 1
day 2
day 28Before hospital discharge
Inclusion/exclusion criteria X
Demographics X
Comorbidities X
Illness severity scores X
Vitals and laboratory data X
ED treatment variables X
ED ventilator data X
ED sedation data X
Depth of sedation* X X X
ICU sedation data X X
Acute brain dysfunction X X
Ventilator, hospital and ICU-free days X
Questionnaire on awareness, memory X
  • *Assessed with Richmond Agitation-Sedation Scale.

  • CAM, confusion assessment method; ED, emergency department; ICU, intensive care unit.