Table 2

Study timeline

Month numberBaselineFollow-up (oral medication arm)Follow-up (prostate surgery arm)
0612182416121824
Singed informed consent
Basic information
 Name
 Age
 BMI
 Education background
 Smoking status
History
 Chief complains
 Medical history
 Current medication status
Questionnaires
 IPSS
 ICIQ-N-QoL
 IIEF
Transrectal ultrasound
Uroflowmetry and post void
 residual
Pressure-flow studyΔΔΔ
Urinalysis
Serum PSA
Blood pressure
Renal function
 Serum creatinine
 Cystatin-C
 eGFR
 BUN
 Uric acid
 β2-MG
 NAG
 Na
 K
 Urine protein
 Urine microprotein/urine
 creatinine ratio
 Urine protein/urine creatinine ratio
Blood lipid
 Cholesterol
 Triglyceride
 High-density lipoprotein
 Low-density lipoprotein
 Lp(a)
Blood glucose
 Fast blood-glucose
 Glycosylated haemoglobin
 Glycated albumin
Adverse events
  • BMI, body mass index; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; ICIQ-N-QoL, international consultation on incontinence questionnaire-nocturia quality of life; IIEF, international index of erectile function; IPSS, International Prostate Symptom Score; NAG, N-acetyl-beta-D-glucosaminidase; PSA, prostate specific antigen.