Table 1

Hodgkin’s lymphoma risk by sex, socioeconomic status and geographical region

Adjusted IRR (95% CI)*
 Risk factorsStudy population≤50 Years>50 YearsMale populationFemale population
Sex
 Male1.30 (1.20 to 1.41)1.23 (1.10 to 1.38)1.38 (1.23 to 1.55)
 P value<0.001<0.001<0.001
Region
 East of England ref ref ref ref ref
 North East England1.42 (1.05 to 1.93)0.82 (0.48 to 1.40)2.05 (1.40 to 3.01)1.49 (1.00 to 2.24)1.34 (0.84 to 2.13)
 Yorkshire/Humber1.32 (1.04 to 1.68)1.11 (0.78 to 1.58)1.55 (1.12 to 2.13)1.48 (1.08 to 2.01)1.15 (0.79 to 1.66)
 London1.29 (1.08 to 1.54)1.15 (0.90 to 1.48)1.45 (1.13 to 1.87)1.25 (0.99 to 1.59)1.33 (1.02 to 1.73)
 South East Coast1.23 (1.03 to 1.48)1.24 (0.96 to 1.59)1.24 (0.97 to 1.59)1.19 (0.94 to 1.51)1.29 (0.99 to 1.69)
 North West England1.07 (0.89 to 1.28)1.05 (0.82 to 1.36)1.07 (0.83 to 1.39)1.13 (0.89 to 1.43)0.99 (0.75 to 1.31)
 South West England1.06 (0.87 to 1.29)1.08 (0.82 to 1.43)1.04 (0.78 to 1.37)1.05 0.81 to 1.36)1.07 (0.80 to 1.43)
 West Midlands1.00 (0.82 to 1.21)0.90 (0.68 to 1.20)1.10 (0.83 to 1.44)0.96 (0.74 to 1.26)1.04 (0.78 to 1.40)
 Wales0.97 (0.80 to 1.18)1.08 (0.83 to 1.42)0.87 (0.65 to 1.15)0.96 (0.74 to 1.25)0.98 (0.73 to 1.32)
 South Central England0.96 (0.80 to 1.15)0.96 (0.75 to 1.24)0.95 (0.73 to 1.23)0.87 (0.68 to 1.11)1.08 (0.82 to 1.42)
 East Midlands0.95 (0.73 to 1.23)1.10 (0.78 to 1.54)0.79 (0.53 to 1.17)0.94 (0.67 to 1.34)0.96 (0.65 to 1.42)
 Northern Ireland0.90 (0.68 to 1.17)0.78 (0.53 to 1.15)1.02 (0.70 to 1.48)0.90 (0.63 to 1.29)0.90 (0.60 to 1.06)
 Scotland0.80 (0.66 to 0.98)0.89 (0.68 to 1.17)0.71 (0.53 to 0.96)0.82 (0.63 to 1.08)0.78 (0.57 to 1.06)
 P value<0.0010.23<0.0010.0020.03
IMD quintile
 5 (most deprived) ref ref ref ref ref
 41.10 (0.96 to 1.26)1.20 (1.00 to 1.45)1.01 (0.83 to 1.23)1.11 (0.92 to 1.34)1.09 (0.89 to 1.33)
 31.15 (1.00 to 1.32)1.12 (0.92 to 1.36)1.18 (0.97 to 1.44)1.21 (1.00 to 1.47)1.08 (0.88 to 1.33)
 21.35 (1.18 to 1.55)1.37 (1.13 to 1.66)1.33 (1.10 to 1.62)1.45 (1.21 to 1.75)1.25 (1.02 to 1.52)
 1 (least deprived)1.60 (1.40 to 1.83)1.55 (1.29 to 1.88)1.63 (1.35 to 1.97)1.87 (1.57 to 2.24)1.31 (1.07 to 1.61)
 P value<0.001†<0.001†<0.001†<0.001†0.003†
  • *Adjusted IRR, Incidence rate ratio adjusted for age, sex, region and IMD quintile.

  • †P value from test for linear trend.

  • IMD, Index of Multiple Deprivation; p, p value from likelihood-ratio test; ref, reference group (East of England used as the reference category as the region with age-standardised incidence estimate that was closest to the national average).