Risk factors for DME using binary logistic regression analysis
| Characteristics | Univariate model | Multivariate model | ||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| DM duration (per year) | 1.036 (1.001 to 1.072) | 0.044* | ||
| BMI (per kg²/m) | 0.914 (0.838 to 0.997) | 0.042* | ||
| SBP (per mm Hg） | 1.023 (1.009 to 1.037) | 0.001** | ||
| Serum urea (per mmol/L) | 1.162 (1.086 to 1.244) | <0.001** | ||
| Scr (per μmol/L) | 1.009 (1.005 to 1.012) | <0.001** | ||
| Urinary protein (per mg/L) | 1.001 (1.000 to 1.001) | <0.001** | ||
| Urinary albumin (per mg/L) | 1.001 (1.001 to 1.002) | <0.001** | ||
| Ucr (per μmol/L) | 0.839 (0.770 to 0.914) | <0.001** | ||
| UACR (per mg/g） | 1.001 (1.001 to 1.001) | <0.001** | ||
| UPCR (per mg/g） | 1.000 (1.000 to 1.000) | <0.001** | ||
| eGFR (per mL/min/1.73 m²) | 0.975 (0.965 to 0.985) | <0.001** | ||
| Stage of UACR (per stage) | 2.449 (1.937 to 3.096) | <0.001** | 2.308 (1.815 to 2.934) | <0.001** |
| Stage of CKD (per stage) | 1.976 (1.516 to 2.574) | <0.001** | ||
| Uric (per μmol/L） | 1.003 (1.001 to 1.006) | 0.015* | ||
| HDL (per mmol/L) | 2.416 (1.143 to 5.107) | 0.021* | ||
| LDL (per mmol/L) | 1.605 (1.212 to 2.124) | 0.001** | 1.460 (1.123 to 1.875) | 0.008** |
| CHOL (per mmol/L) | 1.252 (1.069 to 1.467) | 0.005** | ||
| Lpa (per mg/L) | 1.001 (1.000 to 1.002) | 0.034* | ||
| APOB (per g/L) | 4.849 (1.705 to 13.790) | 0.003** | ||
| ALB (per g/L) | 0.875 (0.827 to 0.925) | <0.001** | ||
| TP (per g/L) | 0.940 (0.897 to 0.984) | 0.009** | ||
Values express as ORs, CI stated at 95% and p value.
All parameters with p≥0.05 were not displayed in this table.
*P<0.05, **p<0.01.
ALB, serum albumin; APOB, apolipoprotein B; BMI, body mass index; CHOL, total cholesterol; CKD, chronic kidney disease; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Lpa, lipoprotein a; SBP, systolic blood pressure; Scr, serum creatinine; TP, total protein; UACR, urine albumin-to-creatinine ratio; Ucr, urinary creatinine; UPCR, urinary protein/Ucr.