Table 1

A priori defined outcome measures

Outcome measureDefinition
Bronchopulmonary dysplasiaNo. of neonates who require oxygen at 36 weeks of postmenstrual age
MortalityDeath before discharge
Severe intraventricular haemorrhageNo. of neonates with grades 3–4 based on the Papile criteria
Air leak syndromesNo. of neonates with pneumothorax or pulmonary interstitial emphysema confirmed by chest X-ray
Retinopathy of prematurity (any stage)No. of neonates with any stage of retinopathy of prematurity as per the international classification of retinopathy of prematurity
Neurodevelopmental impairmentNo. of infants with any degree of neurodevelopmental impairment as assessed by a standardised and validated assessment tool, a child developmental specialist or both, at any age reported (outcome data grouped at 12, 18 and 24 months if available)