Model | Exposure | B (95% CI) | P value | B (95% CI) | P value | B (95% CI) | P value |
Model 1 | TH BMD | −1.812 (−2.475 to −1.149) | <0.001 | ||||
FN BMD | −1.968 (−2.651 to −1.284) | <0.001 | |||||
LS BMD | −0.088 (-0.619 to 0.443) | 0.744 | |||||
Model 2 | Age | 0.064 (0.056 to 0.071) | <0.001 | 0.064 (0.056 to 0.072) | <0.001 | 0.066 (0.058 to 0.073) | <0.001 |
Gender | 0.252 (0.05 to 0.454) | 0.015 | 0.222 (0.023 to 0.422) | 0.029 | 0.166 (−0.037 to 0.37) | 0.109 | |
BMI | −0.066 (−0.09 to −0.041) | <0.001 | −0.07 (−0.094 to −0.046) | <0.001 | −0.072 (−0.097 to −0.048) | <0.001 | |
Smoking | 0.123 (−0.076 to 0.321) | 0.226 | 0.128 (−0.071 to 0.327) | 0.206 | 0.14 (−0.059 to 0.339) | 0.166 | |
CVD | 0.175 (0.005 to 0.344) | 0.044 | 0.178 (0.008 to 0.348) | 0.041 | 0.185 (0.014 to 0.355) | 0.033 | |
DM | 0.519 (0.354 to 0.684) | <0.001 | 0.514 (0.349 to 0.679) | <0.001 | 0.499 (0.334 to 0.664) | <0.001 | |
TH BMD | −0.676 (−1.295 to −0.057) | 0.032 | |||||
FN BMD | −0.509 (−1.133 to 0.115) | 0.109 | |||||
LS BMD | −0.045 (−0.512 to 0.422) | 0.849 | |||||
model 3 | Age | 0.057 (0.047 to 0.067) | <0.001 | 0.058 (0.047 to 0.068) | <0.001 | 0.06 (0.05 to 0.07) | <0.001 |
Gender | 0.281 (0.067 to 0.494) | 0.01 | 0.228 (0.019 to 0.437) | 0.033 | 0.18 (−0.034 to 0.394) | 0.099 | |
BMI | 0.426 (0.261 to 0.591) | <0.001 | 0.418 (0.252 to 0.583) | <0.001 | 0.402 (0.237 to 0.568) | <0.001 | |
Smoking | 0.115 (−0.079 to 0.309) | 0.244 | 0.123 (−0.072 to 0.318) | 0.216 | 0.135 (−0.06 to 0.33) | 0.173 | |
CVD | 0.168 (0.002 to 0.335) | 0.048 | 0.173 (0.006 to 0.34) | 0.043 | 0.18 (0.013 to 0.348) | 0.035 | |
DM | 0.426 (0.261 to 0.591) | <0.001 | 0.418 (0.252 to 0.583) | <0.001 | 0.402 (0.237 to 0.568) | <0.001 | |
SBP | 0.015 (0.01 to 0.02) | <0.001 | 0.015 (0.01 to 0.02) | <0.001 | 0.015 (0.01 to 0.019) | <0.001 | |
HDL-C | −0.316 (−0.571 to -0.061) | 0.015 | −0.322 (−0.578 to −0.066) | 0.014 | −0.333 (−0.589 to −0.077) | 0.011 | |
UA | −0.001 (−0.001 to 0) | 0.24 | −0.001 (−0.001 to 0) | 0.285 | −0.001 (−0.001 to 0) | 0.273 | |
fibrinogen | 0.002 (−0.005 to 0.008) | 0.62 | 0.002 (−0.004 to 0.008) | 0.583 | 0.002 (−0.004 to 0.008) | 0.579 | |
eGFR | 0.003 (−0.09 to 0.096) | 0.945 | 0.004 (−0.09 to 0.097) | 0.935 | 0.005 (−0.089 to 0.099) | 0.917 | |
TH BMD | −0.843 (−1.454 to -0.232) | 0.007 | |||||
FN BMD | −0.563 (−1.174 to 0.048) | 0.071 | |||||
LS BMD | −0.131 (−0.592 to 0.331) | 0.579 |
Table 4 shows results of multiple linear regression analysis between BMD and CAVI. CAVI is the dependent variable.
Model 1: crude model; model 2: adjusted for age, gender, BMI, smoking, history of CVD and history of DM; model 3: adjusted for age, gender, BMI, smoking, history of CVD, history of DM, SBP, HDL-C and blood UA.
B, unstandardised coefficients; BMD, bone mineral density;BMI, body mass index; CAVI, cardio-ankle vascular index; CVD, cardiovascular or cerebrovascular disease; FN FN BMD, femoral neck BMD;HDLC, high-density lipoprotein cholesterol; LS BMD, BMD in the lumbar spine; SBP, systolic blood pressure; TH BMD, total hip BMD; UA, uric acid; eGFR, estimated glomerular filtration rate.