Table 4

Regression analysis with CAVI as the dependent variable

ModelExposureB (95% CI)P valueB (95% CI)P valueB (95% CI)P value
Model 1TH BMD−1.812 (−2.475 to −1.149)<0.001
FN BMD−1.968 (−2.651 to −1.284)<0.001
LS BMD−0.088 (-0.619 to 0.443)0.744
Model 2Age0.064 (0.056 to 0.071)<0.0010.064 (0.056 to 0.072)<0.0010.066 (0.058 to 0.073)<0.001
Gender0.252 (0.05 to 0.454)0.0150.222 (0.023 to 0.422)0.0290.166 (−0.037 to 0.37)0.109
BMI−0.066 (−0.09 to −0.041)<0.001−0.07 (−0.094 to −0.046)<0.001−0.072 (−0.097 to −0.048)<0.001
Smoking0.123 (−0.076 to 0.321)0.2260.128 (−0.071 to 0.327)0.2060.14 (−0.059 to 0.339)0.166
CVD0.175 (0.005 to 0.344)0.0440.178 (0.008 to 0.348)0.0410.185 (0.014 to 0.355)0.033
DM0.519 (0.354 to 0.684)<0.0010.514 (0.349 to 0.679)<0.0010.499 (0.334 to 0.664)<0.001
TH BMD−0.676 (−1.295 to −0.057)0.032
FN BMD−0.509 (−1.133 to 0.115)0.109
LS BMD−0.045 (−0.512 to 0.422)0.849
model 3Age0.057 (0.047 to 0.067)<0.0010.058 (0.047 to 0.068)<0.0010.06 (0.05 to 0.07)<0.001
Gender0.281 (0.067 to 0.494)0.010.228 (0.019 to 0.437)0.0330.18 (−0.034 to 0.394)0.099
BMI0.426 (0.261 to 0.591)<0.0010.418 (0.252 to 0.583)<0.0010.402 (0.237 to 0.568)<0.001
Smoking0.115 (−0.079 to 0.309)0.2440.123 (−0.072 to 0.318)0.2160.135 (−0.06 to 0.33)0.173
CVD0.168 (0.002 to 0.335)0.0480.173 (0.006 to 0.34)0.0430.18 (0.013 to 0.348)0.035
DM0.426 (0.261 to 0.591)<0.0010.418 (0.252 to 0.583)<0.0010.402 (0.237 to 0.568)<0.001
SBP0.015 (0.01 to 0.02)<0.0010.015 (0.01 to 0.02)<0.0010.015 (0.01 to 0.019)<0.001
HDL-C−0.316 (−0.571 to -0.061)0.015−0.322 (−0.578 to −0.066)0.014−0.333 (−0.589 to −0.077)0.011
UA−0.001 (−0.001 to 0)0.24−0.001 (−0.001 to 0)0.285−0.001 (−0.001 to 0)0.273
fibrinogen0.002 (−0.005 to 0.008)0.620.002 (−0.004 to 0.008)0.5830.002 (−0.004 to 0.008)0.579
eGFR0.003 (−0.09 to 0.096)0.9450.004 (−0.09 to 0.097)0.9350.005 (−0.089 to 0.099)0.917
TH BMD−0.843 (−1.454 to -0.232)0.007
FN BMD−0.563 (−1.174 to 0.048)0.071
LS BMD−0.131 (−0.592 to 0.331)0.579
  • Table 4 shows results of multiple linear regression analysis between BMD and CAVI. CAVI is the dependent variable.

  • Model 1: crude model; model 2: adjusted for age, gender, BMI, smoking, history of CVD and history of DM; model 3: adjusted for age, gender, BMI, smoking, history of CVD, history of DM, SBP, HDL-C and blood UA.

  • B, unstandardised coefficients; BMD, bone mineral density;BMI, body mass index; CAVI, cardio-ankle vascular index; CVD, cardiovascular or cerebrovascular disease; FN FN BMD, femoral neck BMD;HDLC, high-density lipoprotein cholesterol; LS BMD, BMD in the lumbar spine; SBP, systolic blood pressure; TH BMD, total hip BMD; UA, uric acid; eGFR, estimated glomerular filtration rate.