BMI trajectory groups | Overall* n=(21 903) | Never-smokers† n=(13 253) | ||||||
Person-years | Deaths | HR | 95% CI | Person-years | Deaths | HR | 95% CI | |
TR1 Lower-normal stable | 52 878 | 655 | 1.00 | 34 655 | 358 | 1.00 | ||
TR2 Higher-normal stable | 96 021 | 1283 | 0.88 | 0.80 to 0.97 | 58 420 | 632 | 0.91 | 0.80 to 1.03 |
TR3 Normal to overweight | 65 825 | 902 | 0.98 | 0.88 to 1.09 | 38 118 | 438 | 1.04 | 0.90 to 1.20 |
TR4 Borderline obesity chronic | 6624 | 124 | 1.21 | 0.99 to 1.47 | 3643 | 65 | 1.36 | 1.04 to 1.79 |
TR5 Normal to class I obesity | 22 598 | 280 | 1.13 | 0.98 to 1.30 | 14 114 | 164 | 1.22 | 1.01 to 1.48 |
TR6 Overweight to class II obesity‡ | 7125 | 83 | 4768 | 50 | ||||
Age 74 years | 1.43 | 1.13 to 1.83 | 1.61 | 1.17 to 2.20 | ||||
Age 80 years | 1.08 | 0.84 to 1.39 | 1.19 | 0.86 to 1.65 | ||||
Age 85 years | 0.85 | 0.62 to 1.17 | 0.93 | 0.62 to 1.39 |
*Adjusted for age, birth cohort, height, sex, country of birth, SEIFA, highest level of education, smoking status at latest BMI assessment, baseline MDS, alcohol drinking status and physical activity score.
†Adjusted for age, birth cohort, height, sex, country of birth, SEIFA, highest level of education, baseline MDS, alcohol drinking status and physical activity score.
‡The p refers interaction between TR6 and attained age=0.0002 for overall and 0.003 for never-smokers, tested using likelihood ratio test.
BMI, body mass index; MDS, Mediterranean Diet Score; SEIFA, Socio-Economic Indexes For Areas.